Partial defects of T-cell development associated with poor T-cell function
نویسندگان
چکیده
منابع مشابه
Hypocalcemia Revealing an Enteropathy-Associated T-cell Lymphoma
Background: Neurofollicular hamartoma (NFH) is characterized histopathologically by fascicles of spindle cells that laterally delimited by hyperplastic folliculosebaceous units. It usually appears on face, near the nose or nasolabial fold. It does not manifest true neural differentiation and recently the term spindle cell predominant trichodiscoma (SCPT) has been used instead. Case Presentatio...
متن کاملDevelopment of a Stable Cell Line, Overexpressing Human T-cell Immunoglobulin Mucin 1
Background: Recent researches have demonstrated that human T-cell immunoglobulin mucin 1 (TIM-1) glycoprotein plays important roles in regulation of autoimmune and allergic diseases, as well as in tumor immunity and response to viral infections. Therefore,targeting TIM-1 could be a potential therapeutic approach against such diseases. Objectives: In this study, we aimed to express TIM-1 protein...
متن کاملArginine reverses T cell defects
An amino acid might help fight chronic hepatitis, according to a study by Das et al. (page 2111). The amino acid arginine is indispensible for the host's T cell response against tumors or chronic infection. Without arginine, a T cell receptor (TCR) component cannot be produced efficiently, thus dampening TCR signaling. As a result, the cells do not proliferate normally or produce the survival c...
متن کاملEffect of ionizing radiation on development process of T-cell population lymphocytes in Chernobyl children
Background: The aim of preliminary study was determined development process status of T-cell population lymphocytes in Ukrainian children after 22 years from Chernobyl accident for next feasibility study. Material and Method: 150 participants aged 6 to 16 years are included in three groups: Group I (n=65), 30 to 60 km from center accident at zone 3th, Group II (n=65) 60 to 90 km from s...
متن کاملDown-Regulation of T Cell Function by Heat Shock-Induced Excretory Factor of Leishmania Major
Background: Despite demonstration of molecular and biochemical changes induced by heat shock on Leishmania, the immunological importance of such changes has not been elucidated. Objective: Studying the effect of two excretory factors prepared under heat shock and ambient temperature from Leishmania major on Balb/c splenocytes function. Methods: The parasites were cultured at 25°C and then sub...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2013
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2013.01.020